Mozzarella Pesto Chicken Grilled Cheese

Featured in: Savory Toasts

This mouthwatering grilled cheese combines shredded chicken breast with bright basil pesto and creamy mozzarella, all pressed between buttered bread until golden and melty. Perfect for a quick lunch or dinner, it takes just 20 minutes total and serves two. Layer your pesto, chicken, and cheese on sourdough or Italian bread, butter the outside, and griddle until crispy and warm. Optional additions like tomato slices, fresh basil, and Parmesan elevate this fusion sandwich to restaurant-quality comfort food.

Updated on Tue, 20 Jan 2026 12:43:00 GMT
A close-up of the golden-brown Mozzarella Pesto Chicken Grilled Cheese, showing melted cheese and shredded chicken peeking from the crispy sourdough crust. Save
A close-up of the golden-brown Mozzarella Pesto Chicken Grilled Cheese, showing melted cheese and shredded chicken peeking from the crispy sourdough crust. | butterhearth.com

My daughter walked in from soccer practice one evening, starving and impatient, and I knew I had about fifteen minutes before a meltdown. I spotted leftover chicken in the fridge, a jar of pesto I'd opened two days earlier, and mozzarella that needed using. What came together in that skillet wasn't just dinner, it was the kind of happy accident that gets requested by name every week after. The smell of toasted sourdough and melting cheese filled the kitchen so fast she actually set the table without being asked.

I made these sandwiches for my book club once, cutting them into quarters like little tea sandwiches, and three people asked for the recipe before we even started discussing the book. One friend admitted she went home and made them that same night. There's something about the way the pesto melts into the mozzarella that makes people lean in and ask what's in there. It's become my go-to whenever I want to look like I tried harder than I actually did.

Ingredients

  • Sourdough or Italian bread: The slight tang of sourdough stands up to the richness of the cheese and pesto, and it crisps beautifully without getting too hard.
  • Fresh mozzarella: This melts into creamy, stretchy strands that hold everything together, avoid the pre-shredded kind if you can because it doesn't melt the same way.
  • Unsalted butter: Softened butter spreads easily and toasts the bread to a deep golden brown without burning, salted butter can make the crust too salty.
  • Cooked, shredded chicken breast: Rotisserie chicken is your best friend here, it's already seasoned and saves you a step.
  • Basil pesto: This is where all the flavor lives, look for one with good olive oil and real Parmesan, or make your own if you have ten minutes.
  • Grated Parmesan cheese: A little sprinkle adds a salty, nutty layer that makes the whole sandwich taste more complex.
  • Small tomato, thinly sliced: Fresh tomato adds a bright, juicy contrast to all the richness, just pat the slices dry so they don't make the bread soggy.
  • Fresh basil leaves: A few whole leaves tucked inside bring a pop of color and a sweet, peppery bite.

Instructions

Spread the pesto:
Lay out all four slices of bread and spread one to one and a half tablespoons of pesto onto two of them, getting it all the way to the edges. This keeps every bite flavorful, not just the middle.
Layer the chicken:
Distribute the shredded chicken evenly over the pesto-covered slices, pressing it down gently so it sticks. If the chicken is cold from the fridge, that's fine, it'll warm through as the sandwich cooks.
Add the cheese and extras:
Lay the mozzarella over the chicken, then tuck in tomato slices and fresh basil if you're using them. Sprinkle Parmesan on top for a little extra sharpness that cuts through the creaminess.
Close the sandwiches:
Place the remaining bread slices on top and press down firmly so everything holds together. You want a compact sandwich that won't fall apart when you flip it.
Butter the outsides:
Spread softened butter on both the top and bottom of each sandwich, covering the entire surface. This is what gives you that deep golden crust and keeps the bread from sticking to the pan.
Grill the sandwiches:
Heat a large skillet over medium heat and place the sandwiches in, pressing them gently with a spatula. Cook for three to four minutes per side until the bread is golden brown and crispy, and the cheese has melted into gooey strands.
Rest and serve:
Remove the sandwiches from the skillet and let them rest for one minute before cutting in half. This gives the cheese a chance to set just slightly so it doesn't all run out when you slice.
Sliced in half, the Mozzarella Pesto Chicken Grilled Cheese reveals a steamy, savory interior of vibrant green pesto and gooey mozzarella on chicken. Save
Sliced in half, the Mozzarella Pesto Chicken Grilled Cheese reveals a steamy, savory interior of vibrant green pesto and gooey mozzarella on chicken. | butterhearth.com

The first time I served this to my husband, he stopped mid-bite and looked at me like I'd been hiding some secret cooking skill for years. It wasn't fancy, it was just bread and cheese and chicken, but something about the way the pesto soaked into everything made it feel special. Now it's the sandwich he requests on his birthday instead of cake, which tells you everything you need to know.

Choosing Your Bread

Sourdough is my favorite because the slight tang balances the richness of the cheese and pesto, but I've made this with ciabatta, multigrain, and even thick-cut white bread when that's all I had. The key is using something sturdy enough to hold up to the butter and the weight of the filling without getting soggy. Avoid thin sandwich bread, it just doesn't have the structure you need. Day-old bread actually works better than fresh because it crisps up without getting too soft in the middle.

Making It Your Own

This sandwich is endlessly adaptable, which is why it's never boring. Swap the chicken for grilled zucchini, roasted red peppers, or sautéed mushrooms for a vegetarian version that's just as satisfying. Try sun-dried tomato pesto instead of basil, or add a handful of baby spinach for extra greens. I've even made it with leftover Thanksgiving turkey and it was so good I almost liked it better than the original meal. Once you get the basic formula down, you can riff on it forever.

Serving Suggestions

I usually serve these with a handful of kettle chips and a simple green salad dressed with lemon and olive oil, something light to balance all that melty cheese. A bowl of tomato soup on the side turns it into the ultimate comfort meal, especially on a rainy afternoon. If you're feeling fancy, pair it with a crisp Italian white wine or sparkling water with a squeeze of lemon. These sandwiches are also great cut into quarters for a casual lunch with friends.

  • Serve with a side of marinara for dipping, it adds a tangy contrast.
  • Try a handful of arugula tucked inside just before serving for a peppery bite.
  • Reheat leftovers in a dry skillet over low heat to bring back the crispiness.
A freshly made Mozzarella Pesto Chicken Grilled Cheese rests on a cutting board, ready to be dipped in marinara sauce for a tangy contrast. Save
A freshly made Mozzarella Pesto Chicken Grilled Cheese rests on a cutting board, ready to be dipped in marinara sauce for a tangy contrast. | butterhearth.com

This sandwich has earned a permanent spot in my weekly rotation, not because it's complicated or impressive, but because it's exactly what I want to eat when I'm hungry and happy. I hope it becomes one of those recipes you make without thinking, the kind that feels like home.

Recipe Questions

Can I use different bread for this sandwich?

Absolutely. While sourdough and Italian bread work beautifully, try ciabatta for a crispier crust or multigrain for added texture and nutrition. Choose bread sturdy enough to hold the fillings without falling apart.

What type of chicken works best?

Cooked chicken breast is ideal for this sandwich. Rotisserie chicken is convenient and flavorful, or you can poach and shred fresh chicken breasts. Make sure the chicken is tender and well-seasoned before layering.

Can I make this sandwich vegetarian?

Yes. Replace the chicken with grilled vegetables like zucchini, roasted red peppers, eggplant, or sun-dried tomatoes. The pesto and mozzarella provide plenty of flavor and richness on their own.

How do I prevent the cheese from leaking out?

Spread pesto and chicken on the bread first to create a base layer, then add cheese on top. Don't overstuff—use the recommended amounts. Cook on medium heat and press gently with a spatula for even melting without overflow.

What should I serve alongside this sandwich?

Pair with a crisp Italian white wine, sparkling water with lemon, or a light salad. Tomato soup complements the pesto and mozzarella flavors beautifully for a classic pairing.

Can I make homemade pesto instead of store-bought?

Homemade pesto is delicious and simple to make. Blend fresh basil, garlic, pine nuts, Parmesan, and olive oil until smooth. Store-bought pesto saves time, but always check labels for allergens like tree nuts and cheese.

Mozzarella Pesto Chicken Grilled Cheese

Golden grilled cheese with juicy chicken, vibrant pesto, and melted mozzarella. Ready in 20 minutes—the perfect savory comfort meal.

Prep duration
10 min
Time to cook
10 min
Complete duration
20 min
Created by Grace Mitchell


Skill Level Easy

Heritage American/Italian Fusion

Output 2 Portions

Dietary considerations None specified

Components

Bread & Dairy

01 4 slices sourdough or Italian bread
02 4 oz fresh mozzarella, sliced or shredded
03 2 tablespoons unsalted butter, softened

Protein

01 1 cup cooked, shredded chicken breast

Sauces & Spreads

01 3 tablespoons basil pesto

Optional Add-Ins

01 2 tablespoons grated Parmesan cheese
02 1 small tomato, thinly sliced
03 Fresh basil leaves

Directions

Stage 01

Prepare bread slices: Lay out bread slices and spread 1 to 1.5 tablespoons pesto onto two of the slices

Stage 02

Layer chicken: Evenly distribute shredded chicken on top of pesto-covered bread slices

Stage 03

Add cheese and toppings: Layer mozzarella cheese over chicken, add tomato slices and fresh basil if using, sprinkle with Parmesan for extra flavor if desired

Stage 04

Assemble sandwiches: Top with remaining bread slices to form complete sandwiches

Stage 05

Butter exterior: Spread softened butter on the outside of each sandwich, covering both top and bottom surfaces

Stage 06

Cook sandwiches: Heat large skillet or grill pan over medium heat, place sandwiches in pan and press slightly with spatula, cook 3 to 4 minutes per side until bread is golden brown and cheese is melted

Stage 07

Finish and serve: Remove from skillet, let rest for 1 minute, cut in half diagonally and serve warm

Necessary tools

  • Large skillet or grill pan
  • Spatula
  • Chef's knife
  • Cutting board

Allergy details

Review each component for potential allergens and consider consulting with a healthcare provider if you're unsure about certain ingredients.
  • Contains dairy: mozzarella, butter, Parmesan cheese
  • Contains gluten: bread
  • May contain tree nuts: verify pesto for pine nuts
  • Store-bought pesto may contain undeclared nut and cheese allergens, review label carefully

Nutritional information (per portion)

These values are estimates only and shouldn't replace professional medical guidance.
  • Energy Value: 520
  • Fats: 27 g
  • Carbohydrates: 32 g
  • Protein Content: 36 g